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New generation producing cell lines

- Provide ready-to-use producing cell lines for use in gene therapy

- Therapeutic genes (e.g. chimeric antigen receptor) will be integrated into the producing cell line using proprietary technology

- Possibility to select vector envelop to achieve selectivity

- Packaging cell lines characteristics:

          * in the absence of chemical induction, cell lines are stable

          * long term culture and freezing of cell lines is possible

          * in response to chemical induction, high level production of vectors for gene therapy

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Stable integration

stable genomic integration into producing cell line

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Silent culture

stable producing cell line

= no vector production without induction

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Induced vector production

high level vector production upon chemical induction

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